Gemini's answer
1. Matt Leinart (QB) | Round 1, Pick 10 (2006)
Perhaps the most famous bust in franchise history, Leinart was a Heisman winner coming off a legendary career at USC. He was expected to be the franchise savior, but he never adjusted to the speed of the NFL.
- The Outcome: He was eventually benched for a veteran Kurt Warner, who led the team to its only Super Bowl appearance. Leinart finished his Cardinals career with more interceptions (20) than touchdowns (14).
2. Levi Brown (OT) | Round 1, Pick 5 (2007)
Brown is often cited as the team’s worst pick because of who was still on the board. The Cardinals chose him to stabilize the offensive line, passing on future Hall of Famers
Adrian Peterson,
Patrick Willis, and
Darrelle Revis.
- The Outcome: Brown struggled immensely with pass protection throughout his tenure, famously allowing 55 sacks and over 300 pressures during his time in Arizona.
3. Josh Rosen (QB) | Round 1, Pick 10 (2018)
The Cardinals traded up to get Rosen, who famously claimed there were "nine mistakes" made ahead of him.
- The Outcome: After a disastrous 3–13 rookie season where he threw 11 touchdowns and 14 interceptions, the team took the unprecedented step of drafting Kyler Murray #1 overall the following year and trading Rosen to the Dolphins. He lasted only one season in Arizona.
4. Andre Wadsworth (DE) | Round 1, Pick 3 (1998)
Wadsworth was a physical specimen from Florida State and was expected to be a perennial Pro Bowler.
- The Outcome: His career was derailed by a long rookie contract holdout followed by chronic knee injuries. He played only 36 games over three seasons, recording just 8 sacks before his NFL career ended prematurely.
5. Jonathan Cooper (OG) | Round 1, Pick 7 (2013)
Cooper was one of the most athletic guard prospects in years, but a broken leg in his first preseason changed the trajectory of his career.
- The Outcome: He never regained the explosive lateral movement that made him a top-10 pick. He was eventually used as a "throw-in" trade piece to the Patriots in exchange for Chandler Jones.