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Winning in MLB on a daily basis is one of the toughest challenges in sports. With 162 games, constant lineup changes, pitching matchups, and the unpredictable nature of baseball, picking winners isn’t about guessing—it’s about analyzing matchups and picking up on patterns. Every day presents a new slate, new opportunities, and new value. From analyzing starting pitchers and bullpen usage to identifying hot lineups and favorable matchups, success comes from staying consistent and trusting the process over the long haul. Here are today’s MLB predictions for final scores and the winners around the league.
MORE: MLB insider Buster Olney ranks the top 5 free agent signings ever
Feb 20, 2026; Sarasota, Florida, USA; Baltimore Orioles starting pitcher Trevor Rogers (28) throws a pitch in the first inning against the New York Yankees during spring training at Ed Smith Stadium. Mandatory Credit: Jonathan Dyer-Imagn Images
Mar 13, 2026; North Port, Florida, USA; New York Yankees starting pitcher Ryan Weathers (40) throws a pitch during the first inning against the Atlanta Braves at CoolToday Park. Mandatory Credit: Kim Klement Neitzel-Imagn Images
MORE: MLB catcher power rankings in week 4
Apr 1, 2026; Milwaukee, Wisconsin, USA; Milwaukee Brewers pitcher Jacob Misiorowski (32) delivers a pitch against the Tampa Bay Rays in the first inning at American Family Field. Mandatory Credit: Michael McLoone-Imagn Images
Mar 19, 2026; Peoria, Arizona, USA; San Diego Padres pitcher Michael King against the Chicago White Sox during a spring training game at Peoria Sports Complex. Mandatory Credit: Mark J. Rebilas-Imagn Images
At the end of the day, picking winners in Major League Baseball is a marathon, not a sprint. There will be bad beats, unexpected blowups, and nights where nothing goes according to plan; that’s the nature of baseball.
The key is staying disciplined, trusting the process, and finding edges over time. Stick with the matchups, follow the trends, and don’t overreact to one slate. We’ll be back with another breakdown, but for now, let’s see how today plays out.
— Enjoy free coverage of the top news & trending stories on The Big Lead —
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MORE: MLB insider Buster Olney ranks the top 5 free agent signings ever
Diamondbacks vs. Orioles
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Feb 20, 2026; Sarasota, Florida, USA; Baltimore Orioles starting pitcher Trevor Rogers (28) throws a pitch in the first inning against the New York Yankees during spring training at Ed Smith Stadium. Mandatory Credit: Jonathan Dyer-Imagn Images
- Pitching Matchup: Kelly vs. Rogers
- Score Prediction: 6-2
- Winner: Orioles
Nationals vs. Pirates
- Pitching Matchup: Mikolas vs. Keller
- Score Prediction: 8-3
- Winner: Pirates
Giants vs. Reds
- Pitching Matchup: Ray vs. Singer
- Score Prediction: 5-3
- Winner: Reds
Royals vs. Tigers
- Pitching Matchup: Ragans vs. Valdez
- Score Prediction: 4-2
- Winner: Tigers
Cubs vs. Phillies
- Pitching Matchup: Rea vs. Nola
- Score Prediction: 6-4
- Winner: Phillies
Angels vs. Yankees
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Mar 13, 2026; North Port, Florida, USA; New York Yankees starting pitcher Ryan Weathers (40) throws a pitch during the first inning against the Atlanta Braves at CoolToday Park. Mandatory Credit: Kim Klement Neitzel-Imagn Images
- Pitching Matchup: Detmers vs. Weathers
- Score Prediction: 4-3
- Winner: Yankees
Marlins vs. Braves
- Pitching Matchup: Meyer vs. Lopez
- Score Prediction: 5-3
- Winner: Braves
Red Sox vs. Twins
- Pitching Matchup: Gray vs. Abel
- Score Prediction: 7-5
- Winner: Red Sox
MORE: MLB catcher power rankings in week 4
Rays vs. White Sox
- Pitching Matchup: McLanahan vs. Schultz
- Score Prediction: 3-2
- Winner: Rays
Jays vs. Brewers
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Apr 1, 2026; Milwaukee, Wisconsin, USA; Milwaukee Brewers pitcher Jacob Misiorowski (32) delivers a pitch against the Tampa Bay Rays in the first inning at American Family Field. Mandatory Credit: Michael McLoone-Imagn Images
- Pitching Matchup: Gausman vs. Misiorowski
- Score Prediction: 5-4
- Winner: Brewers
Guardians vs. Cardinals
- Pitching Matchup: Cantillo vs. McGreevy
- Score Prediction: 6-3
- Winner: Guardians
Rockies vs. Astros
- Pitching Matchup: Lorenzen vs. TBD
- Score Prediction: 8-6
- Winner: Astros
Rangers vs. Athletics
- Pitching Matchup: Gore vs. Springs
- Score Prediction: 4-3
- Winner: Rangers
Mariners vs. Padres
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Mar 19, 2026; Peoria, Arizona, USA; San Diego Padres pitcher Michael King against the Chicago White Sox during a spring training game at Peoria Sports Complex. Mandatory Credit: Mark J. Rebilas-Imagn Images
- Pitching Matchup: Woo vs. King
- Score Prediction: 3-1
- Winner: Padres
Mets vs. Dodgers
- Pitching Matchup: McLean vs. Yamamoto
- Score Prediction: 6-2
- Winner: Dodgers
Conclusion:
At the end of the day, picking winners in Major League Baseball is a marathon, not a sprint. There will be bad beats, unexpected blowups, and nights where nothing goes according to plan; that’s the nature of baseball.
The key is staying disciplined, trusting the process, and finding edges over time. Stick with the matchups, follow the trends, and don’t overreact to one slate. We’ll be back with another breakdown, but for now, let’s see how today plays out.
— Enjoy free coverage of the top news & trending stories on The Big Lead —
Continue reading...