Honestly I don't know if I would do it for any player combo in the draft. I think Bamba is much more of a risk and what happens if you only end up with two really good role players and miss out on a superstar?
I don't even think I would trade the #1 for KAT straight up. I like KAT but I think Ayton might be even better in a few years and plus he's even younger.
I'm more interested in a trade up to get Young/Doncic. Walking away from the draft with Ayton and Young/Doncic makes this team a real contender 3 years from now. A core of Doncic/Young, Booker, Jackson, Bender/Chriss, Ayton is a stronger core than nearly every team in the league not named GSW.