Opening NFL Week 14 Odds and Betting Lines: Lions -3 vs Cowboys on TNF

ASFN Admin · Nov 30, 2025

The calendar flips to December for NFL Week 14, which means the margin for error is extremely slim for those on the playoff bubble and others jockeying for postseason positioning.

The Dallas Cowboys have won three straight and can keep their season alive with a win over the flailing Detroit Lions on Thursday Night Football. While the Lions have looked wobbly of late, they do enter TNF as three-point favorites to kick off the week.

The AFC North is a tire fire that no one seems to want, but, barring a tie, someone will come away as the division leader after the Pittsburgh Steelers and Baltimore Ravens clash on Sunday afternoon, with Lamar Jackson & Co. listed at -6.5.

The Monday Night Football game between the Los Angeles Chargers and Philadelphia Eagles should be a marquee matchup, but the Eagles have dropped two straight, while LAC quarterback Justin Herbert suffered a fracture in his non-throwing hand in Week 13. For now, L.A. is a three-point home underdog.

Here's a look at all of the matchups and NFL odds for Week 14.

NFL odds Week 14

Matchup	Spread	Moneyline	Over/Under
You must be registered for see images Cowboys vs You must be registered for see images Lions	Lions -3	Cowboys +152 Lions -180	54.5
You must be registered for see images Steelers vs You must be registered for see images Ravens	Ravens -6.5	Steelers +265 Ravens -330	45.5
You must be registered for see images Seahawks vs You must be registered for see images Falcons	Falcons +8.5	Seahawks -460 Falcons +360	44.5
You must be registered for see images Titans vs You must be registered for see images Browns	Browns -3.5	Titans +172 Browns -205	34.5
You must be registered for see images Dolphins vs You must be registered for see images Jets	Jets +3	Dolphins -162 Jets +136	41.5
You must be registered for see images Saints vs You must be registered for see images Buccaneers	Buccaneers -7.5	Saints +315 Buccaneers -400	42.5
You must be registered for see images Colts vs You must be registered for see images Jaguars	Jaguars +1.5	Colts -130 Jaguars +110	47.5
You must be registered for see images Commanders vs You must be registered for see images Vikings	Vikings +1.5	Commanders -112 Vikings -104	42.5
You must be registered for see images Bengals vs You must be registered for see images Bills	Bills -5.5	Bengals +235 Bills -290	52.5
You must be registered for see images Broncos vs You must be registered for see images Raiders	Raiders +7.5	Broncos -405 Raiders +320	40.5
You must be registered for see images Bears vs You must be registered for see images Packers	Packers -5.5	Bears +225 Packers -275	45.5
You must be registered for see images Rams vs You must be registered for see images Cardinals	Cardinals +7.5	Rams -450 Cardinals +350	48.5
You must be registered for see images Texans vs You must be registered for see images Chiefs	Chiefs -4.5	Texans +172 Chiefs -205	42.5
You must be registered for see images Eagles vs You must be registered for see images Chargers	Chargers +3	Eagles -166 Chargers +140	41.5

Lines as of 11-30

Cowboys vs Lions odds (Thursday, 8:15 p.m. ET, PRIME)

Opening line

Lions -5.5
Over/Under 54.5
View full Cowboys vs. Lions odds and matchup
Read our Cowboys vs. Lions picks and predictions (coming soon)

Opening line analysis coming soon!

Also see: full Thursday Night Football odds

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