Red Sox at White Sox Prediction: Odds, expert picks, starting pitchers, betting trends and stats for April 11

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Its Friday, April 11 and the Red Sox (6-7) are in the Windy City to take on the White Sox (2-9) in Game 1 of a weekend series.

Sean Newcomb is slated to take the mound for Boston against Davis Martin for Chicago.

The Red Sox salvaged the final game of their series against the Blue Jays with a two-run rally in the bottom of the tenth inning. David Hamilton scored from third when Andres Gimenez could not field a Trevor Story ground ball cleanly and Boston won, 4-3.

The White Sox have not yet won a game in April. They were swept earlier this week by the Guardians losing the finale Thursday, 6-1. Chicago mustered a mere five hits and Jonathan Cannon gave up six runs in 5.1 innings in the loss.

Lets dive into the matchup and find a sweat or two.


We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.


Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.



Game details & how to watch Red Sox at White Sox​

  • Date: Friday, April 11, 2025
  • Time: 7:40PM EST
  • Site: Rate Field
  • City: Chicago, IL
  • Network/Streaming: NESN, CHSN+

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.


Odds for the Red Sox at the White Sox​


The latest odds as of Friday:

  • Moneyline: Red Sox (-169), White Sox (+142)
  • Spread: Red Sox -1.5
  • Total: 8.0 runs


Probable starting pitchers for Red Sox at White Sox​



  • Pitching matchup for April 11, 2025: Sean Newcomb vs. Davis Martin
    • Red Sox: Sean Newcomb (0-1, 5.19 ERA)
      Last outing: 4/6 vs. St. Louis - 4.2IP, 1ER, 6H, 3BB, 5Ks
    • White Sox: Davis Martin (0-1, 5.73 ERA)
      Last outing: 4/5 at Detroit - 5IP, 7ER, 9H, 2BB, 2Ks


Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Red Sox at White Sox​



  • The Red Sox scored 8 runs in their 4-game series against Toronto
  • Despite being just 2-10, The White Sox are 7-5 against the spread
  • It has been 4 games since the Red Sox last covered the Run Line
  • The White Sox have lost 8 in a row
  • Boston's last 4 games have gone UNDER the Game Total


If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!


Expert picks & predictions for tonight’s game between the Red Sox and the White Sox​



Rotoworld Best Bet​



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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.


Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.


Here are the best bets our model is projecting for Friday's game between the Red Sox and the White Sox:

  • Moneyline: NBC Sports Bet is recommending a play on the Boston Red Sox on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago White Sox at +1.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC


Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Brad Thomas (@MrBradThomas)

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