March Madness: NCAA Tournament picks for every Sweet 16 contest

[ASFN Admin]

The second week of the 2025 NCAA Tournament is nearing, and with 16 teams remaining, the bracket has nearly gone chalk.

This week's Sweet 16 will see all four 1-seeds play, and three of the field's four 2-seeds do the same. Of the eight contests set to happen, half of them will see a team that beat a lower-seeded opponent play. However, one of those teams, Michigan, is a 5-seed. Two of them, Ole Miss and BYU, are 6-seeds. Ten-seed Arkansas is the only team still standing that was seeded in the lower half of the field.

Ahead of March Madness's second week, here's a pick-by-pick prediction for the Sweet 16.

Men’s March Madness predictions: Sweet 16​

• Sweet 16 (South Region)
  • 1-seed Auburn over 5-seed Michigan
  • 6-seed Ole Miss over 2-seed Michigan State
• Sweet 16 (East Region)
  • 1-seed Duke over 4-seed Arizona
  • 2-seed Alabama over 6-seed BYU
• Sweet 16(West Region)
  • 1-seed Florida over 4-seed Maryland
  • 3-seed Texas Tech over 10-seed Arkansas
• Sweet 16 (Midwest Region)
  • 1-seed Houston over 4-seed Purdue
  • 2-seed Tennessee over 3-seed Kentucky

Adam Cole is the Auburn athletics beat writer for the Montgomery Advertiser. He can be reached via email at [email protected] or on X, the platform formerly known as Twitter, @colereporter.

This article originally appeared on Montgomery Advertiser: March Madness predictions: Sweet 16 picks for NCAA Tournament

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