Elite Eight Opening Odds: Huskies open as 5.5-point underdogs against Duke

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Mar 27, 2026; Washington, DC, USA;UConn Huskies forward Tarris Reed Jr. (5) dunks the ball against the Michigan State Spartans in the second half during a Sweet Sixteen game of the East Regional of the men's 2026 NCAA Tournament at Capital One Arena. Mandatory Credit: Amber Searls-Imagn Images | Amber Searls-Imagn Images

UConn men’s basketball is back in the Elite Eight for the third time in the last four seasons. The 2-seed Huskies took down 3-seed Michigan State in Washington D.C., leading by as much as 19 but holding on for a 67-63 victory.

Top overall seed Duke awaits UConn on Sunday evening, with the Blue Devils and Huskies facing off at 5:05 p.m. on CBS. For the first time all tournament, UConn is an underdog per FanDuel, with the Huskies giving 5.5 points to Duke. Moneyline odds for a Blue Devils win are -210, while the over/under is set at 134.5.

While Duke is the top overall seed in this year’s tournament, they have struggled to play like it. The Blue Devils avoided a late scare by 16-seed Siena and then beat 9-seed TCU by the skin of their teeth.

Rick Pitino and St. John’s gave Duke all they could handle Friday night, but the Blue Devils’ size and skill eventually won out. The ensuing result is a high-octane Elite Eight matchup between two legendary programs and two of the top coaches in the sport with a Final Four berth on the line.

Following the Michigan State win, UConn’s odds per FanDuel for a seventh national title are now down to +1100, the fifth-best amongst the remaining eight teams. Prior to round one, the Huskies’ odds were +4000. For more NCAA tournament odds and futures, check out FanDuel.

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