2025 NFL Week 12 odds, betting: Full list of Week 12 spreads

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The 2025-26 NFL regular season is past the midway point, and Week 11 saw plenty of upsets as favorites have gone 5-9 against the spread with four outright losses — with the Monday Night Football game still to be played.

It's never too early to look ahead to next week, though, and sportsbooks have already posted lines for every matchup.

Here are the odds for every Week 12 NFL game at BetMGM:

Thursday

Buffalo Bills (-4, 43.5) at Houston Texans

[Check out all of Yahoo's sports betting content here in our new betting hub]

Sunday


1 p.m. ET

Minnesota Vikings at Green Bay Packers (-6, 42)

Pittsburgh Steelers at Chicago Bears (-3, 45.5)

New England Patriots (-7, 50.5) at Cincinnati Bengals

New York Giants at Detroit Lions (-11.5, 49.5)

Seattle Seahawks (-13, 41.5) at Tennessee Titans

Indianapolis Colts at Kansas City Chiefs (-3.5, 49.5)

New York Jets at Baltimore Ravens (-14, 44.5)


4 p.m. ET

Cleveland Browns at Las Vegas Raiders (-3, 37.5)

Jacksonville Jaguars (-2.5, 47.5) at Arizona Cardinals

Philadelphia Eagles (-4.5, 50.5) at Dallas Cowboys

Atlanta Falcons (-1.5, 40) at New Orleans Saints

Sunday Night Football

Tampa Bay Buccaneers at Los Angeles Rams (-6.5, 49.5)

Monday

Carolina Panthers at San Francisco 49ers (-6.5, 47.5)

Bye-week teams: Broncos, Dolphins, Chargers, Commanders

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