Twins at Guardians Prediction: Odds, expert picks, starting pitchers, betting trends and stats for April 29

[ASFN Admin]

Its Tuesday, April 29 and the Twins (13-16) are in Cleveland to take on the Guardians (15-13).

Chris Paddack is slated to take the mound for Minnesota against Tanner Bibee for Cleveland.

Minnesota took the series opener last night throttling Cleveland, 11-1. Ryan Jeffers picked up a couple of hits and drove in three runs to pace the onslaught.

Lets dive into the matchup and find a sweat or two.


We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.


Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Twins at Guardians​

• Date: Tuesday, April 29, 2025
• Time: 6:10PM EST
• Site: Progressive Field
• City: Cleveland, OH
• Network/Streaming: MNNT, CLEG

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Twins at the Guardians​

The latest odds as of Tuesday:

• Moneyline: Twins (+128), Guardians (-153)
• Spread: Guardians -1.5
• Total: 8.0 runs

Probable starting pitchers for Twins at Guardians​

• Pitching matchup for April 29, 2025: Chris Paddack vs. Tanner Bibee
  • Twins: Chris Paddack (0-3, 6.45 ERA)
    Last outing: 4/24 vs. White Sox - 5IP, 2ER, 5H, 4BB, 5Ks
  • Guardians: Tanner Bibee (2-2, 5.19 ERA)
    Last outing: 4/22 vs. Yankees - 6IP, 2ER, 5H, 3BB, 5Ks

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Twins at Guardians​

• The Twins have won 6 of their last 7 games
• The Under is 11-7-2 in Twins' games against AL teams this season
• The Twins have covered in 4 of their last 5 games showing a profit of 3.45 units
• Carlos Correa has hit in 4 straight games (8-15)
• Jose Ramirez 5-22 (.227) over his last 6 games

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Twins and the Guardians​

Rotoworld Best Bet​

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.


Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.


Here are the best bets our model is projecting for Tuesday's game between the Twins and the Guardians:

• Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Minnesota Twins at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC


Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
• Drew Dinsick (@whale_capper)
• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)

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