Possible Alzheimer's prevention breakthrough reported

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  1. Brian in Mesa

    Brian in Mesa BIM™ Contributor

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    May 13, 2002
    The Dark Side
    Possible Alzheimer's prevention breakthrough reported


    Researchers at University of New Mexico researchers believe they may have found a way to prevent Alzheimer's disease, reports CBS Albuquerque affiliate KRQE-TV.

    UNM's Health and Sciences Department Associate Professor Kiran Bhaskar, who's been passionate about studying the disease for the last decade, says the search for a cure started with an idea in 2013.

    "I would say it took about five years or so to get from where the idea generated and get the fully functioning working vaccine," he says.

    Bhaskar and his team started to test the vaccine on mice.

    "We used a group of mice that have Alzheimer's Disease, and we injected them over a series of injections," says PhD student Nicole Maphis.

    Maphis says the vaccine targets a specific protein known as tau that's commonly found in the brains of Alzheimer's patients.

    Maphis was pleased with test results.

    "These antibodies seem to have cleared (out) pathological tau. Pathological tau is one of the components of these tangles that we find in the brains of patients with Alzheimers Disease," she explains. The response lasted for months, UNM says.

    Those long tangles "disrupt the ability of neurons to communicate with one another," the school points out, adding that tau is "normally a stabilizing structure inside of neurons."

    The mice were then given a series of maze-like tests. The mice that received the vaccine performed a lot better than those that hadn't.
    Linderbee likes this.

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