Panthers 2025 game-by-game predictions following schedule release

[ASFN Admin]

It's never too early to predict a full 17-game regular-season schedule, right?

On Wednesday night, the NFL officially revealed the 2025 slate for the Carolina Panthers. And, like every year, fans have already started mapping out their team's potential victories ahead of the upcoming campaign.

So, since we were pretty much bang-on in our 2024 forecast, let's give these game-by-game predictions another go . . .

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Week 1: at Jacksonville Jaguars​

Both of the franchise's NFC championship-winning seasons, 2003 and 2015, successfully began in Jacksonville. While a third trip to the Super Bowl here in 2025 seems rather unlikely, a little bit of history repeats itself once again.

Prediction: Win (22-20)

Week 2: at Arizona Cardinals​

The Panthers and running back Chuba Hubbard eliminated the Cardinals from playoff contention in an overtime thriller last season. Arizona exacts revenge.

Prediction: Loss (23-17)

Week 3: vs. Atlanta Falcons​

No revenge here. After closing up Atlanta's 2024 campaign in a triumphant Week 18 shootout, quarterback Bryce Young and crew keep their division rivals grounded at home.

Prediction: Win (33-25)

Week 4: at New England Patriots​

This time, it's the Panthers—not big-money defensive lineman Milton Williams—who make the Patriots pay.

Prediction: Win (27-16)

Week 5: vs. Miami Dolphins​

If quarterback Tua Tagovailoa can get going, the Miami offense still might have plenty of firepower left to unload.

Prediction: Loss (38-21)

Week 6: vs. Dallas Cowboys​

2025 will mark the Cowboys' third trip to Bank of America Stadium in as many years. They picked up dominant victories in the first two matchups, outscoring the Panthers 63 to 24.

Prediction: Loss (30-20)

Week 7: at New York Jets​

With first-year head coach Aaron Glenn in tow, the Jets might be using 2025 to figure out who they want to be. Dave Canales and the Panthers, meanwhile, may already be there.

Prediction: Win (21-13)

Week 8: vs. Buffalo Bills​

The league's reigning Most Valuable Player and the rest of "Carolina North" may be primed for a Super Bowl run this season.

Prediction: Loss (34-17)

Week 9: at Green Bay Packers​

Carolina's last win at Lambeau Field came back in 2008. They're 0-3 since.

Prediction: Loss (33-24)

Week 10: vs. New Orleans Saints​

Um, who's starting under center for the Saints in 2025?

Prediction: Win (20-10)

Week 11: at Atlanta Falcons​

The Falcons get their lick back.

Prediction: Loss (31-26)

Week 12: at San Francisco 49ers​

Will Carolina's first primetime showcase in two years be a revenge game for running back Christian McCaffrey?

Prediction: Loss (27-14)

Week 13: vs. Los Angeles Rams​

Upset special! The Panthers get a defining win and shock the Rams in a tight battle in Charlotte.

Prediction: Win (24-22)

Week 14: Bye​

Week 15: at New Orleans Saints​

Again, who's playing quarterback for this team?

Prediction: Win (17-13)

Week 16: vs. Tampa Bay Buccaneers​

Tampa Bay has gone 9-1 against Carolina since 2020, and they may have gotten stronger this offseason.

Prediction: Loss (35-24)

Week 17: vs. Seattle Seahawks​

The Panthers stiff-arm the Seahawks in their final home game of the regular season.

Prediction: Win (37-23)

Week 18: at Tampa Bay Buccaneers​

Another year, another series sweep for the class of the NFC South.

Prediction: Loss (41-33)

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This article originally appeared on Panthers Wire: NFL schedule release: Carolina Panthers 2025 game-by-game predictions

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